Polynucleotides are injectable skin-rejuvenation treatments made from purified DNA fragments, usually derived from salmon or trout. They work by stimulating skin repair at a cellular level, improving hydration, elasticity, and overall skin quality rather than adding volume like dermal fillers.
Polynucleotides boost collagen production, improve skin texture, enhance elasticity, and support tissue regeneration. They also help reduce fine lines, improve dull or tired skin, and strengthen the skin barrier for long-term skin health.
Unlike dermal fillers, polynucleotides do not add volume or change facial shape. Instead, they improve skin quality from within by repairing damaged cells and promoting natural regeneration, making them ideal for subtle, natural-looking rejuvenation.
Polynucleotides can be used on the face, neck, décolletage, hands, and under-eye area. They are especially effective for delicate or ageing skin where fillers may not be suitable, such as crepey skin or dark circles under the eyes.
Yes, polynucleotides are considered very safe when administered by a qualified medical professional. They are biocompatible and biodegradable, with a low risk of allergic reactions. Mild swelling or redness at the injection site is common but usually temporary.
Results typically develop gradually over several weeks as collagen production increases. The benefits can last up to 6–9 months, depending on the treatment area, skin condition, and individual lifestyle factors. Maintenance treatments are often recommended.
Most treatment plans involve a course of 2–3 sessions spaced 2–4 weeks apart. This allows the skin to regenerate progressively and achieve optimal, long-lasting results.
Polynucleotides are suitable for most adults looking to improve skin quality, hydration, and early signs of ageing. They are particularly popular with patients seeking natural rejuvenation without added volume or dramatic changes to facial structure.
