Polynucleotides
Our clinicians will thoroughly explain your procedure and answer any questions you may have. We will create a bespoke treatment plan tailored to your needs.
Summary Guide
Duration: 15 – 30 minutes
Treatment Protocol: 3 sessions, 2–3 weeks apart
Anaesthetic: optional cream but not typically required
Downtime: none
Noticeable results: ~4–6 weeks
Length of results: ~6 months
Polynucleotides are a cutting-edge injectable treatment designed to support skin regeneration at a cellular level. Derived from highly purified DNA fragments—most commonly sourced from salmon—they work by activating fibroblasts, the cells responsible for producing collagen, elastin, and hyaluronic acid. This regenerative process helps to restore skin texture, firmness, and hydration over time. Polynucleotides also enhance microcirculation and calm inflammation, creating an optimal environment for skin repair.
Treatments are minimally invasive, well-tolerated, and ideal for those seeking subtle, natural improvements in skin quality with little to no downtime.

At The Oxley, we tailor every treatment to your unique anatomy and skin needs. Polynucleotides are an excellent complement to other aesthetic treatments, enhancing overall skin quality and supporting long-term skin health by promoting natural regeneration from within.
Polynucleotides are commonly used to enhance skin quality in delicate areas such as the under-eyes, cheeks, neck, and décolletage. They are particularly effective for addressing fine lines, crepey texture, dullness, and the early signs of skin ageing. In some patients, they may also improve overall skin tone, texture, and support repair in sensitive or previously damaged skin. Thanks to their regenerative properties, polynucleotides offer a subtle yet powerful approach to natural, progressive skin rejuvenation.